The Australian International School opened on 1 February 1993 at its first campus on Mount Sophia, an area behind Plaza Singapura and the Cathay Building reconstruction. The school started under the leadership of Miss Coral Dixon with 32 students and 7 teachers, with no air-conditioning, uniform or facilities that are now taken for granted. By the end of 1993, there were over two hundred students.

The School experienced rapid growth and by the end of 1994, with numbers just over 400, the students moved to Emerald Hill, directly behind Orchard Road . Although the School was bigger and could accommodate more students it still did not have a full–sized gym, pool, theatre and other much needed facilities.

As the School continued to expand it was clear that space was running out at Emerald Hill and by the end of 1997, AISS had moved to Ulu Pandan, near Clementi, the site of the old Singapore American School, which had recently moved to a new site at Woodlands.

The School enjoyed five and a half years at Ulu Pandan during which time it finally secured land to construct a purpose built school at Lorong Chuan, with first class facilities. In April 2002, Mr Peter Bond began as Principal of AISS.

The School moved from Ulu Pandan to its final “home” at Lorong Chuan over the holidays in July 2003, with 1100 students enrolled. Currently there are 1750 students enrolled and the School employs around 140 members of the teaching staff.